Grab one in three would die without

Grab Attention Coach, Tommy Hilfiger, Gucci,Victoria’s Secret. Sounds familiar? Do you know the story behind of how these brands’ products were made? I bet you that you won’t think twice when purchasing products from companies that have used animal testing. Did you know that approximately 26 million animals in the United States are used for commercial and scientific testing? Put yourselves in their shoes. Imagine if you were used as a “lab rat” instead, helplessly going through the physical and mental torture just to find cures and used for research of another living thing. Should animals’ lives be deemed less “worthy” than humans’?-          Reveal topic: Define   So, what is animal testing? Animal testing refers to any experiment performed on a live animal ,where they are forced to undergo something that tortures them mentally and physically.    They have also been used since 500 BC to develop a treatment for diseases and to check on product safety for human use . Laboratory animals are deliberately harmed without benefiting them, and are usually killed at the end of the experiment. ( use this for intro and reasons) –          Suffering of animals-          Preview main points by introducing 2 other grp members (what they gna talk abt)  (pros and cons for animal testing)    2 reasons for argumentAnimal testing contributed to many life saving cures and treatments. We humans share 95% of our genes with a mouse, making them an effective model for the human body1.How Animal testing benefits us from kidney failureAverage of 5,000 people who develop kidney failure each year in the UK, one in three would die without regular dialysis or a transplant.The animal experimentsAmong the scientists involved in this experiment was Joseph E. MurraySurgical techniques for transplantation were perfected in dogs and pigs in the 1950s before it became routine in humans. However, rejection of new organ remained a problem.As Cyclosporine, which is extracted from a species of fungus, was discovered in 1972 and found to be a strong immune suppressor in mice. Later on was tests in humans found that it prolonged the survival of transplant kidneys. Research on transplants in dogs showed that combining cyclosporine with steroid produces a three-fold increase in survival time.Why animals?It would be impossible to perfect surgical techniques without the help of animal testingWhat’s it done for humans?About 2,000 kidney patients each year was benefit from kidney transplants and more would do so if more organs were available.2. How Animals testing benefits us from Breast cancerAs for Breast cancer will affect one in 11 women during their lifetime and affects around 40,000 women each year in the UK.The animal experimentsAnimal studies in the 1950s showed that hormone changes can influence breast tumors in rats. Which led to the development of TamoxifenTamoxifen is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men which helps to blocks the growth of hormone dependent breast cancers. Further research with mice showed its possible preventive role.Why animals?The initial use of animals here has now meant an alternative to animals for breast cancer research. Tamoxifen work showed that lab grown cultures of human tumor cells will respond to drugs that are effective in patients. Without animal work it may not have been possible to show that the cell culture results were relevant and reliable. Animal studies, mainly rats and mice, have also been crucial in the development of monoclonal antibody treatments such as Herceptin.What’s it done for humans?Breast cancer is now the second most survivable female cancer, with a 77% five-year survival rate. Tamoxifen was introduced in the 90s, which lead to 30% fall in death rates. Now it has  proved that tamoxifen can also prevent breast cancer in high-risk women. 2 reasons against argumentIt caused the animals to be burned, shocked, poisoned, isolated, starved, drowned, addicted to drugs, and brain-damage.Even when alternatives to the use of animals are available, the law does not require that they be used—and often they aren’t. Experimenters force-feed chemicals to animals, conduct repeated surgeries on them, implant wires in their brains, crush their spines, and much more. After enduring these terrifying, painful procedures, animals are then usually dumped into a cage without any painkillers.  Animals not only suffer from pain but also suffer severe stress from day-to-day testing laboratory. Research shows that mice are able to understand when watching other mice in agony and get influence by it. An undercover lab examination also disclose that monkeys frenziedly spinning around in laboratory cages, ripping out their hairs, biting wounds and injuring themselves due to the never ending emotional distress they must endure during the tests. A term to describe is, “stress-induced psychosis”. The testings in the laboratory are driving these animals crazy.According to the Food and Drug Administration report shows that 92 out of every 100 drugs that pass animal tests fail in humans. sum up, our group has concluded that animal testing should not be legalised. Although we humans benefit greatly from experimenting on animals, such as finding a cure to illness, we should not neglect  it harms the animal and bringing them to suffer what they do not deserve and end up giving up their lives for these testings. Furthermore, animal testing does not suit everyone of us. In the US, more than 106,000 human die every year negative reactions through animal testings and causing injuries to 2.2million of humans. “Mice are mice, human are human. If we look to the mouse to model every aspect of disease for humans and to model cures, we are just wasting our time.”